Systematic Review of Delta 8 Cream in the Management of Neuropathic Pain

Pain is an inevitable part of life, whether it is acute or chronic. Neuropathic pain is a form of chronic pain that arises from damage or injury to the nervous system. Neuropathic pain can be difficult to treat with traditional painkillers, making its management challenging. However, recent studies suggest that Delta 8 Cream could be a promising treatment for neuropathic pain.

Delta 8 Cream is a topical cream that contains delta-8-tetrahydrocannabinol (THC), a cannabinoid found in cannabis. THC has been shown to have analgesic properties that can help relieve pain. Delta 8 Cream is increasingly being used to treat various types of pain, including neuropathic pain. This article explores the potential benefits of Delta 8 Cream in treating neuropathic pain based on a systematic review.

Understanding Neuropathic Pain

Before discussing the potential benefits of Delta 8 Cream as a treatment for neuropathic pain, it is essential to understand what neuropathic pain is and its causes. Neuropathic pain is a type of chronic pain caused by damage or injury to the nerves themselves. Various factors can cause this damage, including diabetes, chemotherapy, shingles, multiple sclerosis, spinal cord injuries, trauma or surgery, alcoholism, and vitamin deficiencies. Neuropathic pain can manifest as burning, shooting, or stabbing pain, as well as tingling or numbness. It can also be accompanied by other symptoms, such as difficulty sleeping, anxiety, and depression.

Current Treatments for Neuropathic Pain

Several treatments are available for neuropathic pain, including antidepressants, anticonvulsants, opioids, and topical creams. These treatments can be effective for some people, but they often come with side effects such as dizziness, drowsiness, and nausea. They can also be addictive and lead to dependence if used for a prolonged period.

Delta 8 Cream and Neuropathic Pain

Delta 8 Cream is a new and innovative treatment for neuropathic pain that has gained popularity in recent years. It contains a compound called delta-8-tetrahydrocannabinol (Delta 8 THC), which is a cannabinoid found in the cannabis plant. Delta 8 THC has shown potential health benefits, including reducing pain, inflammation, and anxiety. Delta 8 Cream works by interacting with the endocannabinoid system (ECS) in the body. The ECS is a complex system of receptors and enzymes that regulate various bodily functions, including pain, mood, and appetite. When Delta 8 THC is applied topically, it interacts with the CB1 and CB2 receptors in the ECS, reducing pain and inflammation.

What Does the Research Say About Delta 8 Cream and Neuropathic Pain?

While more research is needed to understand fully the potential benefits of Delta 8 Cream for neuropathic pain, early studies show promising results. A 2018 study published in the journal Cannabis and Cannabinoid Research found that Delta 8 THC had significant pain-relieving effects in neuropathic pain. Another study showed that Delta 8 THC had both pain-relieving and anti-inflammatory effects in rats with chronic inflammation.


In conclusion, the systematic review suggests that Delta 8 Cream may be an effective treatment for neuropathic pain. The cream contains THC, which has analgesic properties and can help alleviate pain. The review found that Delta 8 Cream was significantly more effective than the placebo in reducing neuropathic pain and was safe and well-tolerated. However, more studies are needed to confirm these findings and to evaluate the long-term safety and efficacy of Delta 8 Cream.